Guide for new business and research ideas
The project ideas reflect the capacity of the five partner organizations to promote research results for new project proposals, while including the contact data of the project’s responsible.
6. Presentation of the 30 project ideas in template
6.3. Bioimplant used in gastroenterology
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Action |
Content |
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Title of the project |
Bioimplant used in gastroenterology |
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Envisaged Program for funding / other sources for funding |
EUROSTAR,EUREKA,M-ERA NET
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Domain of interest |
Medical Textiles
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Abstract (up to 500 words) |
Surgical meshes are currently used for the treatment of various types of hernias: primary abdominal wall hernias (inguinal hernia, femoral hernia, umbilical hernia),secondary hernias (post-incisional). The project will develop functionalized bioimplants for the treatment of hernias and eventrations in gastroenterology correlated to advanced surgical techniques that means : identification of eventration, selection of biomaterial. Mesh produced from polypropylene multifilament yarn has disadvantage : it does not provide structural support required to support abdominal muscles in case of hernias and eventrations ; it requires additional reinforcement. The project will provide meshes with high density and high porosity that will assure smooth healing of the wound. The raw materials (polyester, polypropylene etc.) ensure: high biocompatibility, low relapse rate of eventration with a structure that have no adverse reaction or rejection. The functionalization with natural polymers: chitosan, collagen, alginates by encapsulation and dedicated protocol for incorporation into the textile material are in view. Biological determinations and biocompatibility tests: mutagenic potential assessment, sensitizing potential, implant tests: biocompatibility: cytotoxicity, sensitization, acute systemic toxicity, genotoxicity, implantation, hemocompatibility, chronic and sub-chronic toxicity, carcinogenicity ;hematologic characteristics : hematocroi, hemoglobin, leucocite, lucocitare formula etc. will be provide. |
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Keywords (up to 5) |
Eventration, mesh, functionalization, natural polymers
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Envisaged partners sought |
Research institutes, universities, private textile companies, hospitals |
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Contact data (Name/Surname, Organization, email) |
Visileanu Emilia The Research and Development Institute for Textiles and Leather visilean@ns.certex.ro |
